Farkon gano ciwon suga tun yana yara!!

Farkon gano ciwon suga tun yana yara!!

Masu bincike sun yi nazari kan jinin yaran da ke da dabi'ar dabi'ar halitta don bunkasa nau'in ciwon sukari na XNUMX kuma sun gano wani rukunin sunadaran da ke yin hasashen kamuwa da cutar kansa, wanda aka yi imanin zai haifar da cutar watanni kafin bayyanar cututtuka, a cewar wani rahoto da gidan yanar gizon "New Atlas" ya buga. , nakalto wani rahoto. Cell Reports Medicine.

Don fahimtar abubuwan da ke haifar da abubuwa da hanyoyin

A cikin nau'in ciwon sukari na 1, tsarin garkuwar jiki yana kaiwa hari tare da lalata ƙwayoyin beta masu ɓoye insulin a cikin pancreas, yanayi ne na yau da kullun, wanda ba zai iya warkewa ba wanda ke shafar miliyoyin mutane a duniya, amma abubuwan da ke haifar da amsawar autoimmune wanda ke haifar da shi ba a fahimta sosai. .

Proteomics

A cikin proteomics, ana amfani da proteomics, a tsakanin sauran abubuwa, don bincika lokacin da kuma inda aka bayyana sunadaran, hulɗa da yadda suke shiga cikin hanyoyin rayuwa. Binciken furotin zai iya ba da hanyar gano alamun cututtukan cututtuka.

Sakamakon bincike, wanda masana kimiyya suka gudanar daga dakin gwaje-gwaje na kasa na Pacific Northwest National Laboratory (PNNL) a Washington, sun ba da rahoton yuwuwar masu gano kwayoyin halitta waɗanda zasu iya gano tsarin autoimmune wanda ke haifar da nau'in ciwon sukari na 1.

Sakamako masu kayatarwa

Thomas Metz, wani mai bincike a kan binciken, ya ce "abin farin ciki ne game da wannan aikin da ya bude kofa na gano rigakafi da wuri fiye da yadda ake da shi a yanzu, wanda ke ba da damar samun karin bayani game da abin da ke sa tsarin rigakafi ya kunna jiki." kuma sakamakon zai iya taimakawa wajen fahimtar hanyoyin.” An fi fahimtar rawar da ke taka rawa wajen ci gaban ciwon sukari fiye da yadda ake yi a halin yanzu kuma yana ba da damar yin amfani da hanyoyin warkewa.”

Pancreas na ɗan adam ya ƙunshi nau'ikan sel masu ɓoye hormone, ɗaya daga cikinsu shine ƙwayoyin beta. A halin yanzu, babu wata hanyar da za a iya tantance ko mutumin da ya kamu da kwayar cutar zai sami kariya ta jiki ga kananan kwayoyin halitta, yana lalata su kuma ta haka ne ke haifar da ciwon sukari na 1, kamar yadda galibi ana yin ganewar asali ne lokacin da majiyyaci ya gabatar da su zuwa asibiti ko ofishin likita lokacin da suka rigaya. suna da ciwon sukari Alamomin hawan jini.

matakin ganowa

Binciken na yanzu an yi shi ne a matakai biyu, na farko shi ne lokacin ganowa, masu binciken sun yi nazarin samfuran jini 2252 da aka tattara akai-akai daga yara 184 daga haihuwa zuwa shekaru shida suna shiga cikin Matsalolin Muhalli na Ciwon sukari a cikin Nazarin Matasa. Masu binciken sun gano sunadaran sunadarai 376 da aka canza a cikin yara waɗanda aka nuna suna da yanayin ƙwayar cuta zuwa ciwon sukari.

Matakin tabbatarwa

Mataki na biyu shine matakin tabbatarwa, wanda masu binciken suka bincika samfuran plasma na jini 6426 daga yara 990, ta amfani da na'urar koyo algorithm don taimakawa aiwatar da adadi mai yawa na samfura, da ƙungiyar sunadaran 83 waɗanda ke hasashen tsarin sauye-sauye a cikin yara. wadanda suka ci gaba da bunkasa rigakafi, an gano su. An gano sunadaran watanni kafin bayyanar cututtuka.
Masu binciken dai sun ce binciken ne mafarin aiki ne da suke fatan za a iya hasashen wadanda za su kamu da cutar sikari ta 1, kuma sun shirya ci gaba da nazarin jinin da aka dauka daga yaran da aka yi binciken har zuwa shekaru 15.

Ƙarin cikakkun gogewa

Ana buƙatar ƙarin bincike don tabbatar da sakamakon da kuma ganin ko binciken ya shafi kowa da kowa, ba yara kawai ba, wanda aka zaɓa daga binciken da ke da kwayoyin halitta don ciwon sukari.

Masu bincike sun ce ana tantance na'urar da ke gano cutar kansa kuma tana ba da ikon sa ido kan majiyyaci don tabarbarewar lafiya da kuma haifar da ƙarin kulawar likita cikin gaggawa, tun kafin bayyanar cututtuka ta bayyana.

Ernesto Nakiasu, wani mai bincike a kan binciken ya ce "A wannan mataki, ƙungiyar masu bincike suna ƙoƙarin fahimtar yadda za a iya yin hasashen ciwon sukari," in ji Ernesto Nakiasu, wani mai bincike a kan binciken, yana mai cewa "a ƙarshe, makasudin zai kasance don hana ƙananan ƙwayoyin da ke samar da insulin daga lalacewa kuma ta haka ne ya hana. ciwon sukari."

Hasashen horoscope na Maguy Farah na shekarar 2023