Pehea e pale aku ai nā keiki iā Covid-19?

Pehea e hakakā ai nā keiki iā COVID-19 ؟

Ua pale nui nā keiki i nā hōʻailona koʻikoʻi o COVID-19 no ka mea he ikaika ko lākou "innate" immune pane e hoʻopau koke i ka maʻi. Akā ua ʻike nā mea noiʻi mai ka "Garvan Institute for Medical Research", ʻaʻole like me nā pākeke, ʻaʻole hoʻomanaʻo nā ʻōnaehana pale o nā keiki i ka maʻi SARS-CoV-2, ʻo ia hoʻi, ʻaʻole lākou e hoʻomohala i kahi hoʻomanaʻo adaptive e pale aku i ka maʻi me ia, no laila ke ua ʻike ʻia lākou i ka maʻi maʻi, pili ke kino o ke keiki iā ia ma ke ʻano he hoʻoweliweli hou, e like me ka mea i paʻi ʻia e News Medical, e ʻōlelo ana i ka Clinical Immunology.

ʻO ka "naivety" o ka ʻōnaehana pale

ʻO ke kumu "ʻaʻole i ʻike ʻia nā keiki i nā maʻi maʻi he nui, no laila ikaika loa ko lākou ʻōnaehana pale," wahi a Prof. "naive." Ma muli o ka hoʻomohala ʻole ʻana o nā keiki i nā pūnaewele T hoʻomanaʻo, ua pilikia lākou e loaʻa hou i ka maʻi.

Hōʻike ʻo Polofesa Fan me kēlā me kēia hanana maʻi maʻi hou i ka ulu ʻana o ke keiki, aia kahi pilikia e lilo ai kā lākou mau T-cell i 'maloʻo' a ʻaʻole pono, e like me nā T-cell o ka poʻe ʻelemakule, ʻo ia ke kumu he mea nui ka hoʻopaʻa ʻana. keiki.

ʻElua mau ʻano o ka ʻōnaehana pale, ʻo ka ʻōnaehana pale kūlohelohe ka laina mua o ka pale ʻana, ʻo ia hoʻi nā pale kino e like me ka ʻili a me nā ʻili mucous e pale ai i nā maʻi mai ke komo ʻana. Loaʻa iā ia nā cell e hana i nā kemika e hoʻouna i nā hōʻailona i nā cell ʻē aʻe a pale aku i nā maʻi maʻi. Akā ʻaʻole ʻokoʻa ka ʻōnaehana immune innate ma waena o kekahi ʻano virus a i ʻole kekahi.

ʻO ka laina ʻelua o ka pale ʻana i nā cell B a me T o ka ʻōnaehana immune adaptive. Loaʻa i kēia mau pūnaewele nā ​​mea loaʻa kikoʻī hiki ke ʻike a hoʻokaʻawale i nā ʻāpana like ʻole o ka maʻi a hoʻopuka i kahi pane wikiwiki e hoʻokaʻawale a hōʻemi paha iā lākou.

Ua ʻike ka poʻe noiʻi ʻo nā ʻōnaehana pale ʻana o nā pēpē e like me ka "blank slate" me ka hapa nui o nā cell T naive. Ke neʻe nei lākou i ka wā kamaliʻi a hiki i ka wā makua a loaʻa i nā maʻi maʻi ʻē aʻe, ua pani ʻia ko lākou naive T cell e nā cell T memory i hiki ke pane i nā maʻi a lākou i ʻike mua ai.

Ua wehewehe ʻo Associate Professor Philip Britton, ke kauka maʻi infectious pediatric ma Westmead Children's Hospital: "Ke hele nei nā ʻōnaehana pale o nā keiki mai ka hilinaʻi nui ʻana i ka ʻōnaehana innate, a i ka makemake ʻana i ka ʻōnaehana adaptive ma ke ʻano he kākoʻo i ka wā e ulu ai lākou a no laila ʻaʻole hiki ke hoʻomaʻemaʻe i nā maʻi. ".

pilikia i ka ʻelemakule

ʻO ka mea mahalo, ʻo nā hopena o ka noiʻi e hōʻike ana ʻo ke kumu o ka maʻi ʻelemakule he ʻano o ka hopena immune nui loa i ka maʻi SARS-CoV-2, e like me kā Professor Fan i ʻōlelo ai "i ka wā e loaʻa mua ai nā pākeke me ka maʻi SARS-CoV-2. , ʻike ko lākou mau pūnana T hoʻomanaʻo i ka mea a lākou i ʻike ai ma mua, no ka laʻana, kahi ʻāpana maʻamau o ka coronavirus e noho pū ana me nā maʻi anu maʻamau, "i ʻōlelo ai ʻo ia, e wehewehe ana ma muli paha o ka ʻōnaehana pale" ʻAʻole i kikoʻī ʻia ka SARS-CoV-2, e hāʻawi ana i kahi manawa no ka maʻi e pakele ai a hoʻonui i ka ʻike ʻole ʻia e hoʻokau i nā hōʻailona koʻikoʻi aʻe e piʻi ana ka ʻōnaehana pale e hoʻoponopono i ka pilikia.

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