He lapaʻau no nā poʻe maʻi hānō e hoʻemi ana i kona hopena ʻino

He lapaʻau no nā poʻe maʻi hānō e hoʻemi ana i kona hopena ʻino

ʻO ka hoʻohana ʻana i kahi lāʻau lapaʻau e hōʻemi ai i ka ʻāʻī o ka ʻāʻī i hiki ai i ka 92% o ka poʻe me ka hānō koʻikoʻi e hōʻemi i kā lākou mau lā i kēlā me kēia lā o nā steroid inhaled me ka ʻole o ka hōʻeha ʻana i ko lākou mau hōʻailona, ​​​​ua loaʻa kahi noiʻi hou. ʻO kēia mau ʻike e hiki i nā poʻe me ka hānō koʻikoʻi ke hōʻemi i ka hopena o nā hopena ʻino e pili ana i ka hoʻohana ʻana i ka steroid lōʻihi, e like me New Atlas, e haʻi ana i ka Lancet.

Ma kahi o 300 miliona mau kānaka me ka hānō ma ka honua nei, ma kahi o 3% a 5% ka loaʻa ʻana o ka hānō koʻikoʻi, e ʻike ana i ka pōkole o ka hanu i kēlā me kēia lā, ka umauma a me ka ʻū e alakaʻi pinepine ai i ka haukapila. ʻO ka hapa nui o nā maʻi hānō koʻikoʻi he subtype i kapa ʻia eosinophilic asthma, ʻo ia ka mea i hōʻike ʻia e nā kiʻekiʻe kiʻekiʻe o nā cell immune (eosinophils) i loko o ke koko e hoʻoulu ai i ka pehu ʻole a me ka mumū o nā alaloa.

E pale i nā hopena maikaʻi ʻole

ʻO ka lāʻau lapaʻau i manaʻo ʻia no ka hānō eosinophilic, e like me ka Global Initiative for Asthma (GINA), he hui i kēlā me kēia lā o budesonide (he corticosteroid inhaled e mālama i ka mumū) a me formoterol (he bronchodilator lōʻihi e hoʻomaha a wehe i nā alaloa). ʻO kēia lāʻau lapaʻau, i ʻike ʻia he ICS a i ʻole "steroid," ʻoi aku ka maikaʻi ma mua o nā mea hoʻopakele "hoʻopakele" pōkole ma muli o kāna mau hopena anti-inflammatory a me ka bronchodilator. Akā, hiki i ka hoʻohana lōʻihi ke pilikia, no ka mea, pili ia i ka maʻi o ka waha, ka osteoporosis, ka maʻi maʻi diabetes, kahi ʻōnaehana pale nāwaliwali, a me nā cataracts.

ʻO kahi haʻawina, i alakaʻi ʻia e nā ʻepekema mai King's College London ma luna o nā maʻi ma nā ʻāina ʻehā: ʻo United Kingdom, Farani, Italia a me Kelemānia, nānā ʻia inā ʻo ka mālama ʻana me benralizumab (kahi lāʻau olaola) hiki i ka poʻe me ka hānō eosinophilic koʻikoʻi ke hōʻemi i ka nui o ka ICS me ka ʻole o ka nalowale. ka mālama ʻana i ko lākou mau hōʻailona.

Ua ʻōlelo ʻo David Jackson, ke alakaʻi o ka hui noiʻi: "Ua hoʻololi nā lāʻau lapaʻau e like me benralizumab i ka mālama ʻana i ka maʻi hānō ma nā ʻano he nui, a ʻo nā hopena o ka noiʻi hou e hōʻike ana no ka manawa mua e hiki ke pale ʻia ka pōʻino pili i ka steroid no ka hapa nui. nā maʻi e hoʻohana nei i kēia lāʻau lapaʻau.

Hāʻawi ʻia ʻo Benralizumab e ka subcutaneous injection i hoʻokahi manawa i kēlā me kēia ʻehā pule no nā kau mua ʻekolu, a laila hoʻokahi manawa i kēlā me kēia ʻewalu pule.

Ua hōʻike ʻia nā hopena o ke aʻo ʻana, ma ka laulā, 92% o nā mea komo i hōʻemi i ka nui o ICS. ʻO ka mea kikoʻī, 15% o lākou i hōʻemi i ka maʻi i kahi haʻahaʻa haʻahaʻa, 17% i kahi haʻahaʻa haʻahaʻa, a me 61% i kahi maʻa e like me ka mea e pono ai. Eia kekahi, 91% o ka poʻe i komo ʻaʻole i ʻike i ka piʻi ʻana o nā hōʻailona i ka wā tapering.

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