Wax ka baro hoormoonka mas'uulka ka ah faafinta kansarka dhiigga

Ma xisaabin karno sababaha keena kansarka, maadaama uu yahay kiimiko ay ku lug leeyihiin kun arrimood, laakiin cilmi-baaris dhawaan Ingiriis ah ayaa lagu ogaaday in hormoonka stress-ka ee bini'aadamka ama "cortisol" ay tahay arrin weyn oo ka dambeysa fashilka nidaamka difaaca si looga hortago kansarka dhiigga. .

Daraasadan ayaa waxaa sameeyay cilmi-baarayaal ka tirsan jaamacadda Kent ee dalka Britain, waxayna natiijadooda ku daabaceen cadadkiisii ​​ugu dambeeyay ee joornaalka Cellular and Molecular Immunology.

Kooxdan oo uu hogaaminayo Dr. Vadim Sumbaev, ayaa markii ugu horeysay daaha ka qaaday in unugyada leukemia-ga ee aadka u daran ay ka baxsadaan nidaamka difaaca iyaga oo qoraya hormoonka dadka ee cortisol.

Kooxdan oo daraasaddooda diiradda ku saartay sababaha cudurkan, ayaa sheegay in kansarka dhiigga uu isticmaalo dariiq u gaar ah horumarka jidhka, iyadoo la adeegsanayo hababka shaqada ee jidhka bini'aadamka si ay u taageeraan badbaadada unugyada, iyo sidoo kale hoos u dhigista hawlaha difaaca jidhka bini'aadamka. -kansar.

Daraasadu waxay kaloo cadaysay in leukemia uu isticmaalo hormoonka cortisol si uu jidhku ugu qasbo inuu soo saaro borotiinka "latrophyllin 1", taas oo iyaduna keenta in la soo saaro borotiin kale oo loo yaqaan "galectin 9" kaas oo xakameynaya habka dabiiciga ah ee ka hortagga kansarka.

Kooxda Sumbayev oo la shaqaynaysay cilmi-baarayaal ka kala socday laba jaamacadood oo Jarmal ah, waxay ogaadeen in inkasta oo unugyada dhiiga cad ee caafimaadka qaba aysan saameyn ku yeelan cortisol, ay awoodaan inay sii daayaan borotiinka latrophyllin-1 marka uu qofku ku dhaco leukemia.

Daraasadu waxay ku soo gabagabaysay in galectin-9, iyo sidoo kale latrophylin-1, oo ah laba borotiino oo laga helo balasmaha dhiiga bini'aadamka, ayaa ah bartilmaameedyo rajo leh oo loogu talagalay daaweynta difaaca si loola dagaallamo leukemia ba'an ee myeloid leukemia mustaqbalka.

"Markii ugu horeysay, waxaan aqoonsan karnaa dariiqo awood noo siinaya mustaqbalka inaan horumarino daaweyn cusub oo wax ku ool ah iyadoo la adeegsanayo hababka difaaca dabiiciga ah ee jirka si loola dagaallamo leukemia," ayuu yiri Sumbaev. Nolosha iyo ka baxsanaanta weerarka difaaca.

Cudurka 'myeloid leukemia' ee ba'an wuxuu ka sameysmaa dhuuxa lafta waxayna keentaa tirada korodhka unugyada dhiigga cad ee dhiigga.

Marka loo eego qiyaasaha Machadka Kansarka Qaranka ee Mareykanka, ku dhawaad ​​21 xaaladood oo ah cudurka leukemia ba'an ee 'myeloid leukemia' ayaa sanadkan laga ogaan doonaa gudaha Mareykanka.