Meriana ena e ka baka lera la mahlo

Meriana ena e ka baka lera la mahlo

Le hoja matšoao a k'holeseterole e phahameng maling a tiisa bothata ba pono, sehlopha sa bo-rasaense se fihletse qeto ea hore bakuli ba nang le liphatsa tsa lefutso tse amanang le lithethefatsi tsa statin ba na le kotsi e eketsehileng ea ho tšoaroa ke lera.

Liphuputso tse fetileng tsa lipatlisiso li bontšitse hore ho na le bopaki bo bong ba hore li-statins li ka eketsa kotsi ea ho ba le lera, ho ea ka The Print, e qotsa Journal of the American Heart Association (JAHA).

li-statins feela

Leha phuputso ea morao-rao e bontša hore bafuputsi ba fumane hore liphatsa tsa lefutso tse etsisang tšebetso ea li-statins le tsona li ka eketsa kotsi ea ho ba le lefu la cataract.

Ba hlalositse hore lithethefatsi tsena hangata li fokotsa maemo a LDL cholesterol ka ho thibela enzyme e bitsoang HMG-CoA-reductase (HMGCR).

Leha ho le joalo, lipatlisiso tsa mahlale li netefalitse hore mefuta e fapaneng sebakeng sa liphatsa tsa lefutso tsa HMGCR ho genome ea motho e ama tsela eo bakuli ba sebelisang cholesterol ka eona.

Ka lehlakoreng le leng, mofuputsi ea ka sehloohong oa thuto, Moprofesa Jonas Jahaus, molekane oa Cardiac Genetics Group ho Molecular Cardiology Laboratory Lefapheng la Biomedical Sciences Univesithing ea Copenhagen, Denmark, o tlalehile hore phuputso e ne e sitoa ho fumana kamano leha e le efe pakeng tsa tse ncha. Lithethefatsi tse seng tsa statin le litlhare tse tloaelehileng. Ho fokotsa lipid le kotsi ea cataract, ka hona ho ka etsahala hore phello ena e amana haholo le li-statins.

Leha ho le joalo, o ile a hatisa bohlokoa ba melemo ea li-statins ho fokotsa maemo a tlaase a lipoprotein tse tlaase ho batho ba nang le k'holeseterole e phahameng, a hlalosa hore li feta likotsi tse nyenyane tsa ho ba le lefu la cataract.

Mefuta e 5 e tloaelehileng ea liphatsa tsa lefutso

Bafuputsi ba ile ba sekaseka lintlha tsa liphatsa tsa lefutso tsa batho ba fetang 402,000, ba shebane le mefuta e mehlano ea liphatsa tsa lefutso tse neng li tsejoa e le tse fokotsang LDL cholesterol.

Lintlha tsa liphatsa tsa lefutso li ile tsa baloa ho ipapisitsoe le phello e boletsoeng esale pele ea mofuta o mong le o mong ho LDL-cholesterol. Lintlha tsa liphatsa tsa lefutso tsa liphatsa tsa lefutso li ile tsa hlahlojoa ho khetholla bajari ba phetoho e sa tloaelehang ho HMGCR e bitsoang phetoho e lebeletsoeng ea tahlehelo ea mosebetsi.

Moprofesa Jahaus o itse: "Ha re e-na le phetoho ea ho lahleheloa ke mosebetsi, phatsa ea lefutso ha e na monyetla oa ho sebetsa." Haeba lefutso la HMGCR le sa sebetse, 'mele o ke ke oa etsa protheine ena. Ka mantsoe a bonolo feela, phetoho e sa sebetseng ho phatsa ea lefutso ea HMGCR e lekana le ho nka statin. ”
lintlha tsa kotsi tsa lefutso

Liphello tsa phuputso li senoletse hore likotsi tsa liphatsa tsa lefutso ka lebaka la HMGCR li etsa hore batho ba be le monyetla o moholo oa ho ba le lefu la cataract.

E 'ngoe le e' ngoe ea 38.7 mg / dL e fokotseha ho LDL-cholesterol ka lintlha tsa liphatsa tsa lefutso e ne e amahanngoa le kotsi e eketsehileng ea 14% ea ho ba le cataract le 25% e eketsa kotsi ea ho kenella ka ho buuoa.

Phello e ntle

Ha e le phello e ntle, bafuputsi ba tlaleha hore moeli o moholo oa thuto ke hore le hoja ho jara mefuta ena ea liphatsa tsa lefutso ho beha kotsi ea bophelo bohle ba ho ba le cataract, kotsi ena ha ea lokela ho hlahlojoa ka tsela e tšoanang ho batho ba qalileng ho nka li-statins hamorao bophelong. Li-statins, tse fokotsang boemo ba k'holeseterole maling. Ho hlokahala tlhahlobo e eketsehileng ea mokhatlo ona litekong tse ngata tsa bongaka ho netefatsa liphuputso tsena.

Hoa hlokomeleha hore thibelo ea k'holeseterole e phahameng le likotsi tseo e li bakang ho na le mekhoa e 'maloa, ea bohlokoa ka ho fetisisa e leng ho etsa liphetoho tsa bophelo le ho ikoetlisa kamehla, ha u ntse u khomarela phepo e nepahetseng, le ho se tsube.

Hammoho le ho latela ngaka haeba ho na le kotsi le ho khomarela lengolo la ngaka ho qoba ho hlaha ha mathata a kotsi.