Uphononongo luqinisekisa ukuba i-Alzheimer's inokosulela phakathi kwabantu

Uphononongo luqinisekisa ukuba i-Alzheimer's inokosulela phakathi kwabantu

Iingcali zenzululwazi zisanda kufumana ubungqina bokuqala bokuba isifo se-Alzheimer, unobangela ophambili we-dementia edla ngokwenzeka ngenxa yokuguga, inokudluliselwa phakathi kwabantu.

Uphononongo luqinisekisile ukuba abantu abahlanu bahlakulela i-Alzheimer's besebancinci, phakathi kweminyaka engama-38 kunye ne-55, emva kokufumana iihomoni ezithathwe kwiingqondo zabaxhasi abafayo, kwaye abanye abathathu babonisa iimpawu zokulimala kwengqondo okanye ukulahlekelwa yimemori, ngokutsho kwephephandaba iThe Sun.

Unyango lwe-hormone yokukhula komntu lwanikwa ubuncinane abantwana abali-1800 abaneengxaki zokukhula phakathi ko-1959 no-1985. Olu nyango lwayekiswa kuba lwabangela ukuba ezinye izigulana zibe nesifo esibulalayo i-Creutzfeldt-Jakob, esaziwa ngokuba sisifo senkomo esiphambeneyo, esisisifo esingaqhelekanga esichaphazela ... ingqondo kwaye ikhokelela kukuphazamiseka kwengqondo.

Esi sifo safunyanwa kwiminyaka emva kokutofwa kweeproteni ezingcolisekileyo, kwaye kumashumi eminyaka kamva, ezinye iisampulu zafunyaniswa ukuba zinetyhefu ye-amyloid beta proteins, eziluphawu lwesifo i-Alzheimer's.

Iingcali zenzululwazi ngoku zikholelwa ukuba iqela laba bantwana liye laphuhliswa yi-dementia kwiminyaka ephakathi ngenxa yokudluliselwa kweeprotheni ezinobungozi ezivela ebuchotsheni babanikeli abaswelekileyo.

Umbhali wophononongo uGqr. Gargi Banerjee, weYunivesithi yaseLondon College, wachaza: “Sifumanise ukuba kunokwenzeka ukuba i-amyloid beta pathology idluliselwe kwaye ibe negalelo kwisifo sika-Alzheimer, kwaye olu sulelo lwenzeka emva kokunyangwa ngokuphindaphindiweyo ngezinto ezingcolileyo, ngokufuthi kwiminyaka eliqela. ”

Iingcali zigxininisa ukuba oku akuthethi ukuba i-Alzheimer's inokudluliselwa ngayo nayiphi na enye indlela okanye ngenkqubo yonyango efana notofelo-gazi okanye ukufakelwa kwelungu.

UNjingalwazi uAndrew Doig, weYunivesithi yaseManchester, wathi: “Olu hlobo lutsha lwesifo sika-Alzheimer lubangela umdla omkhulu kwinzululwazi, kodwa akukho sizathu sakoyika.

Indlela esabangelwa ngayo esi sifo yayekwa kwiminyaka engaphezu kwama-40 eyadlulayo.

UGqr Bart de Strooper, weDementia Research UK, wongezelela esithi: “Akukho mntu ufanele acinge ngokutsha okanye ayeke naluphi na unyango lwezamayeza, ingakumbi utofelo-gazi okanye utyando lwemithambo-luvo olusindisa ubomi babantu abaninzi kangaka nyaka ngamnye.”

Uphononongo, olupapashwe kwiphephancwadi i-Nature Medicine, lathi kunokwenzeka ukuba inani elikhulu labantu liya kuhlakulela isifo se-Alzheimer ngale ndlela.

Kwelakhe icala, uGqr. Susan Koolhaas, ovela kwi-Alzheimer's Research UK, wathi: “Olu phononongo luye lwatyhila ngakumbi malunga nendlela amaqhekeza e-amyloid asasazeka ngayo ngaphakathi kwengqondo, kwaye oku kusinika imikhondo engakumbi malunga nendlela isifo sika-Alzheimer esikhula ngayo kunye neethagethi ezintsha ezinokubakho kunyango lwexesha elizayo. ”

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