Izifundo zamva nje, unyango olusebenzayo lweswekile

Kubonakala ngathi le ntlekele ingasonjululwanga iza kuphela kungekudala, njengoko abaphandi baseJapan bebhengeze ukufumanisa kwabo indlela entsha esekwe ekulawuleni ukusebenza kwe-enzyme esibindini, enokukhokelela kunyango olusebenzayo lohlobo lwe-XNUMX yeswekile.
Uphononongo lwenziwe ngabaphandi kwiYunivesithi yaseKanazawa eJapan, kwaye iziphumo zabo zapapashwa kwiphepha lamva nje lejenali yenzululwazi yezoNxibelelwano lweNdalo.

Iqela lophando lenze uphando kwiqela leempuku ekuzameni ukuqonda indlela emva kwemeko yeshukela ephezulu emva kokutya.
Iqela longezelela ukuba le meko ininzi isiphumo sokungahambi kakuhle kwesibindi sokufunxa i-glucose, kwaye ichaphazela izigulane ezinesifo seswekile se-II kunye nokukhuluphala, kwaye kukhokelela kumngcipheko okhulayo wezifo zentliziyo.
Nangona indlela ebangela ukufunxwa kweglucose engasebenziyo ingekaziwa, kukho ubungqina bokuba ibangelwa kukuphazamiseka kwi-enzyme ye-glucokinase yesibindi.
Kwaye i-glucokinase yenye ye-enzymes yesibindi, ekhawulezayo kwaye iququzelele inkqubo yokuguqula i-glucose ibe "i-glucose-6-phosphate", eyona nqanaba lokuqala le-glycolysis.
Kuphononongo lwabo olutsha, abaphandi bakwazi ukuchonga i-enzyme ebizwa ngokuba yi-Sirt2 edlala indima ephambili ekulawuleni isenzo se-glucokinase ye-hepatic ngokujongana nokungaqhelekanga kwi-absorption yesibindi ye-glucose.
Abaphandi bathi ukuqonda le ndlela kunye nokulawula isenzo sale enzyme kunokubonisa injongo yonyango esebenzayo yohlobo lwe-XNUMX yeswekile kunye nokukhuluphala.
Bongeze ukuba baqaphele ukuba iimpuku ezinesifo seswekile se-XNUMX nazo zityebe kakhulu, kwaye unyango lokungaqhelekanga lokufunxa iswekile yesibindi kunokumisa ukunyuka kweswekile yegazi emva kokutya.
Ngokutsho koMbutho wezeMpilo weHlabathi, malunga ne-90% yeemeko ezibhalisiweyo zesifo seswekile emhlabeni luhlobo lwe-XNUMX, olubonakala ikakhulu ngenxa yobunzima kunye nokungabikho kokuzivocavoca umzimba, kwaye ngokuhamba kwexesha, izinga eliphezulu leswekile egazini linokunyusa. umngcipheko wesifo sentliziyo, ubumfama, imithambo-luvo kunye nokusilela kwezintso.
Ngokwahlukileyo koko, uhlobo loku-XNUMX lweswekile lwenzeka xa inkqubo yomzimba yokuzikhusela itshabalalisa iiseli ezilawula umlinganiselo weswekile esegazini, ingakumbi ebantwaneni.

Umbutho ubonise ukuba abantu abazizigidi ezingama-422 kwihlabathi jikelele banesifo seswekile, kwaye uMmandla waseMpuma weMeditera unesabelo sabantu abazizigidi ezingama-43.